|
|
2-isopropylmaleate + H2O <=> (2S)-2-isopropylmalate
|
4.2.1.33
3-isopropylmalate dehydratase
|
–
|
| |
BRENDA:
BR413;
BR49521;
BS1964
KEGG:
R03968;
R04001
MetaCyc:
3-ISOPROPYLMALISOM-RXN;
RXN-8991
SABIO-RK:
3704;
3736
|
|
|
|
2-isopropylmaleate + H2O <=> (2S)-2-isopropylmalate
|
4.2.1.33
3-isopropylmalate dehydratase
|
–
|
| |
BRENDA:
BR413;
BR49521;
BS1964
KEGG:
R03968;
R04001
MetaCyc:
3-ISOPROPYLMALISOM-RXN;
RXN-8991
SABIO-RK:
3704;
3736
|
|
|
|
(2R,3S)-3-isopropylmalate + NAD+ <=> (2S)-2-isopropyl-3-oxosuccinate + NADH + H+
|
1.1.1.85
3-isopropylmalate dehydrogenase
|
–
|
| |
BRENDA:
BR47597;
BS373119
KEGG:
R04426
MetaCyc:
3-ISOPROPYLMALDEHYDROG-RXN
|
|
|
|
H+ + (2S)-2-isopropyl-3-oxosuccinate <=> 4-methyl-2-oxopentanoate + CO2
|
0.0.0.0
1.1.1.85
3-isopropylmalate dehydrogenase
|
–
–
|
| |
BRENDA:
BR52894
KEGG:
R01652
MetaCyc:
RXN-7800
|
|
|
|
2-oxoisovalerate + acetyl-CoA + H2O <=> H+ + (2S)-2-isopropylmalate + CoA
|
2.3.3.13
2-isopropylmalate synthase
2.3.3.17
methylthioalkylmalate synthase
|
–
–
|
| |
BRENDA:
BR47381;
BS353415;
BS375022;
BS438748
KEGG:
R01213
MetaCyc:
2-ISOPROPYLMALATESYN-RXN
SABIO-RK:
545
|
|
|
|
4-methyl-2-oxopentanoate + H+ <=> Isovaleraldehyde + CO2
|
4.1.1.1
pyruvate decarboxylase
4.1.1.7
benzoylformate decarboxylase
4.1.1.72
branched-chain-2-oxoacid decarboxylase
|
–
–
–
|
| |
BRENDA:
BS363284
MetaCyc:
RXN-7692
|
|
|
|
3-methyl-1-butanol + NAD+ <=> Isovaleraldehyde + NADH + H+
|
1.1.1.1
alcohol dehydrogenase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.265
3-methylbutanal reductase
|
–
–
–
|
| |
BRENDA:
BR26045-a
KEGG:
R05685
MetaCyc:
1.1.1.265-RXN_WOP;
RXN-7693
SABIO-RK:
5281
|
|
